PD. Dr. med. Isabel Frielitz-Wagner
Universität zu Lübeck
Ratzeburger Allee 160
23538 Lübeck
Publications
I.
Wagner,
I.
Savchuk,
L.
Sahlin,
A.
Kulle,
N.
Klöting,
A.
Dietrich,
P.
Holterhus,
J.
Dotsch,
M.
Bluher, and
O.
Söder,
De Novo and Depot-Specific Androgen Production in Human Adipose Tissue: A Source of Hyperandrogenism in Women with Obesity, Obes Facts , vol. 15, no. 2, pp. 281-291, 2022.
De Novo and Depot-Specific Androgen Production in Human Adipose Tissue: A Source of Hyperandrogenism in Women with Obesity, Obes Facts , vol. 15, no. 2, pp. 281-291, 2022.
| DOI: | 10.1159/000521571 |
I.
Wagner,
N.
Klöting,
I.
Savchuk,
L.
Eifler,
A.
Kulle,
S.
Kralisch-Jacklein,
J.
Dotsch,
O.
Hiort,
K.
Svechnikov, and
O.
Söder,
Diabetes Type 1 Negatively Influences Leydig Cell Function in Rats, Which is Partially Reversible By Insulin Treatment, Endocrinology , vol. 162, no. 4, 2021.
Diabetes Type 1 Negatively Influences Leydig Cell Function in Rats, Which is Partially Reversible By Insulin Treatment, Endocrinology , vol. 162, no. 4, 2021.
| DOI: | 10.1210/endocr/bqab017 |
J.
Jeschke,
C.
Biagioni,
T.
Schierling,
I.
Wagner,
F.
Borgel,
D.
Schepmann,
A.
Schuring,
A.
Kulle,
P.
Holterhus,
M.
Wolff,
B.
Wunsch,
V.
Nordhoff,
T.
Strunker, and
C.
Brenker,
The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn(2+) on CatSper Ca(2+) Channels in Human Sperm, Front Cell Dev Biol , vol. 9, pp. 699554, 2021.
The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn(2+) on CatSper Ca(2+) Channels in Human Sperm, Front Cell Dev Biol , vol. 9, pp. 699554, 2021.
| DOI: | 10.3389/fcell.2021.699554 |
C.
Brenker,
C.
Schiffer,
I.
Wagner,
F.
Tuttelmann,
A.
Ropke,
A.
Rennhack,
U.
Kaupp, and
T.
Strunker,
Action of steroids and plant triterpenoids on CatSper Ca(2+) channels in human sperm, Proc Natl Acad Sci U S A , vol. 115, no. 3, pp. E344-E346, 2018.
Action of steroids and plant triterpenoids on CatSper Ca(2+) channels in human sperm, Proc Natl Acad Sci U S A , vol. 115, no. 3, pp. E344-E346, 2018.
| DOI: | 10.1073/pnas.1717929115 |
I.
Wagner,
L.
Sahlin,
I.
Savchuk,
N.
Klöting,
K.
Svechnikov, and
O.
Söder,
Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats, Obesity (Silver Spring) , vol. 26, no. 7, pp. 1161-1167, 2018.
Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats, Obesity (Silver Spring) , vol. 26, no. 7, pp. 1161-1167, 2018.
| DOI: | 10.1002/oby.22198 |
L.
Eifler,
A.
Hoffmann,
I.
Wagner,
N.
Klöting,
L.
Sahlin,
T.
Ebert,
B.
Jessnitzer,
U.
Lössner,
M.
Stumvoll,
O.
Söder,
M.
Fasshauer, and
S.
Kralisch,
Leptin restores markers of female fertility in lipodystrophy, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , vol. 1864, no. 10, pp. 3292-3297, 2018.
Leptin restores markers of female fertility in lipodystrophy, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , vol. 1864, no. 10, pp. 3292-3297, 2018.
| DOI: | 10.1016/j.bbadis.2018.07.015 |
A.
Hoffmann,
G.
Manjowk,
I.
Wagner,
N.
Klöting,
T.
Ebert,
B.
Jessnitzer,
U.
Lössner,
J.
Stukenborg,
M.
Blüher,
M.
Stumvoll,
O.
Söder,
K.
Svechnikov,
M.
Fasshauer, and
S.
Kralisch,
Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model, Endocrinology , vol. 157, no. 6, pp. 2461-2468, 2016.
Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model, Endocrinology , vol. 157, no. 6, pp. 2461-2468, 2016.
| DOI: | 10.1210/en.2015-1966 |
I.
Wagner,
N.
Klöting,
N.
Atanassova,
I.
Savchuk,
C.
Spröte,
W.
Kiess,
O.
Söder, and
K.
Svechnikov,
Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats, Molecular and Cellular Endocrinology , vol. 437, pp. 154-162, 2016.
Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats, Molecular and Cellular Endocrinology , vol. 437, pp. 154-162, 2016.
| DOI: | 10.1016/j.mce.2016.08.027 |
K.
Landgraf,
D.
Rockstroh,
I.
Wagner,
S.
Weise,
R.
Tauscher,
J.
Schwartze,
D.
Loffler,
U.
Buhligen,
M.
Wojan,
H.
Till,
J.
Kratzsch,
W.
Kiess,
M.
Bluher, and
A.
Korner,
Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children, Diabetes , vol. 64, no. 4, pp. 1249-61, 2015.
Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children, Diabetes , vol. 64, no. 4, pp. 1249-61, 2015.
| DOI: | 10.2337/db14-0744 |
| File: | db140744.pdf |
I.
Wagner,
M.
Sabin,
R.
Pfaffle,
A.
Hiemisch,
E.
Sergeyev,
A.
Korner, and
W.
Kiess,
Effects of obesity on human sexual development, Nat Rev Endocrinol , vol. 8, no. 4, pp. 246-54, 2012.
Effects of obesity on human sexual development, Nat Rev Endocrinol , vol. 8, no. 4, pp. 246-54, 2012.
| DOI: | 10.1038/nrendo.2011.241 |

- People
- Leadership
- SFB 1665 Office
- Principal Investigators
- Busch, Hauke
- Frielitz-Wagner, Isabel
- Göpel, Wolfgang
- Hiort, Olaf
- Holterhus, Paul-Martin
- Hornig, Nadine
- Hundt, Jennifer E.
- Jürgensen, Martina
- Kircher, Martin
- König, Inke R.
- Krämer, Ulrike
- Kulle, Alexandra
- Laudes, Matthias
- Mangold, Anna Katharina
- Malich, Lisa
- Mittag, Jens
- Müller, Franz-Josef
- Nemec, Birgit
- Palm, Kerstin
- Rehmann-Sutter, Christoph
- Reisch-Pawlu, Nicole
- Seeger, Karsten
- Spielmann, Malte
- Stammberger, Birgit
- Stoff, Heiko
- Research Associates
- PhD candidates
- Clinicians
- Coordination
- Technical Staff
- Involved Institutions and Departments
- Former Employees
