PD. Dr. med. Isabel Frielitz-Wagner

Photo of Isabel  Frielitz-Wagner

Universitätsklinikum Magdeburg, Universitätskinderklinik


Otto-von-Guericke-Universität Magdeburg
Leipziger Straße 44
39120 Magdeburg

Email: isabel.frielitz-wagner(at)med.ovgu.de
Phone: +49 391 67-24112

Publications

I. Wagner, I. Savchuk, L. Sahlin, A. Kulle, N. Klöting, A. Dietrich, P. Holterhus, J. Dotsch, M. Bluher, and O. Söder,
De Novo and Depot-Specific Androgen Production in Human Adipose Tissue: A Source of Hyperandrogenism in Women with Obesity, Obes Facts , vol. 15, no. 2, pp. 281-291, 2022.
DOI:10.1159/000521571
I. Wagner, N. Klöting, I. Savchuk, L. Eifler, A. Kulle, S. Kralisch-Jacklein, J. Dotsch, O. Hiort, K. Svechnikov, and O. Söder,
Diabetes Type 1 Negatively Influences Leydig Cell Function in Rats, Which is Partially Reversible By Insulin Treatment, Endocrinology , vol. 162, no. 4, 2021.
DOI:10.1210/endocr/bqab017
J. Jeschke, C. Biagioni, T. Schierling, I. Wagner, F. Borgel, D. Schepmann, A. Schuring, A. Kulle, P. Holterhus, M. Wolff, B. Wunsch, V. Nordhoff, T. Strunker, and C. Brenker,
The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn(2+) on CatSper Ca(2+) Channels in Human Sperm, Front Cell Dev Biol , vol. 9, pp. 699554, 2021.
DOI:10.3389/fcell.2021.699554
C. Brenker, C. Schiffer, I. Wagner, F. Tuttelmann, A. Ropke, A. Rennhack, U. Kaupp, and T. Strunker,
Action of steroids and plant triterpenoids on CatSper Ca(2+) channels in human sperm, Proc Natl Acad Sci U S A , vol. 115, no. 3, pp. E344-E346, 2018.
DOI:10.1073/pnas.1717929115
I. Wagner, L. Sahlin, I. Savchuk, N. Klöting, K. Svechnikov, and O. Söder,
Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats, Obesity (Silver Spring) , vol. 26, no. 7, pp. 1161-1167, 2018.
DOI:10.1002/oby.22198
L. Eifler, A. Hoffmann, I. Wagner, N. Klöting, L. Sahlin, T. Ebert, B. Jessnitzer, U. Lössner, M. Stumvoll, O. Söder, M. Fasshauer, and S. Kralisch,
Leptin restores markers of female fertility in lipodystrophy, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease , vol. 1864, no. 10, pp. 3292-3297, 2018.
DOI:10.1016/j.bbadis.2018.07.015
A. Hoffmann, G. Manjowk, I. Wagner, N. Klöting, T. Ebert, B. Jessnitzer, U. Lössner, J. Stukenborg, M. Blüher, M. Stumvoll, O. Söder, K. Svechnikov, M. Fasshauer, and S. Kralisch,
Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model, Endocrinology , vol. 157, no. 6, pp. 2461-2468, 2016.
DOI:10.1210/en.2015-1966
I. Wagner, N. Klöting, N. Atanassova, I. Savchuk, C. Spröte, W. Kiess, O. Söder, and K. Svechnikov,
Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats, Molecular and Cellular Endocrinology , vol. 437, pp. 154-162, 2016.
DOI:10.1016/j.mce.2016.08.027
K. Landgraf, D. Rockstroh, I. Wagner, S. Weise, R. Tauscher, J. Schwartze, D. Loffler, U. Buhligen, M. Wojan, H. Till, J. Kratzsch, W. Kiess, M. Bluher, and A. Korner,
Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children, Diabetes , vol. 64, no. 4, pp. 1249-61, 2015.
DOI:10.2337/db14-0744
File: db140744.pdf
I. Wagner, M. Sabin, R. Pfaffle, A. Hiemisch, E. Sergeyev, A. Korner, and W. Kiess,
Effects of obesity on human sexual development, Nat Rev Endocrinol , vol. 8, no. 4, pp. 246-54, 2012.
DOI:10.1038/nrendo.2011.241